Bladder Instillations with a Combination of Hyaluronic Acid and Chondroitin Sulfate in Bladder Pain Syndrome Patients: Preliminary Results of a 12 Weeks Administration Schedule

Hypothesis / aims of study Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC) is a complex condition that requires multimodal, multidisciplinary and scaled therapeutic approach. Several studies have shown that glicosaminglycans (GAGs) replenishment therapy improves pain, urinary symptoms and quality of live of patients with BPS/CI. Some authors found good efficacy in BPS/IC patients refractory to others therapies [1]. The primary objective of this study is to evaluate our initial experience in terms of efficacy and safety, with 12 weeks bladder instillations of a commercial combination of hyaluronic acid and chondroitin sulfate (Ialuril®) in patients with BPS/IC. A secondary objective was to compare efficacy in primary and refractory BPS/IC patients.